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BIOENGINEER.ORG - Bioengineering
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News
Engineered T Cell Receptors With Built-In ICOS Deliver Long-Lasting
6+ min ago (120+ words) Adoptive T cell therapy has delivered striking remissions in some blood cancers, but its promise in solid tumors has been repeatedly undermined by a stubborn problem: the therapeutic cells do not last. Engineered T cells that flood a tumor and…...
Scientists Flip the Drug Discovery Pipeline to Put Human Biology First in
10+ min ago (704+ words) Cardiovascular medicine is quietly undergoing a structural rethink, and the change begins with the order of operations....
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing
10+ min ago (55+ words) Gene editing has long promised a revolution in cancer medicine, yet the promise has remained stubbornly out of reach for one deceptively simple reason: getting the CRISPR-Cas9 machinery into tumor cells, and only tumor cells, is extraordinarily difficult. A new…...
ApoA2 Drives Metastasis and Drug Resistance in Liver Cancer Through
10+ min ago (541+ words) A protein long considered a quiet passenger in the bloodstream has been caught playing a far more sinister role in liver cancer....
Low Muscle Mass Emerges as a Powerful Predictor of Death in Cancer Patients
10+ min ago (704+ words) A sweeping analysis of more than 635,000 cancer patients in South Korea has delivered one of the clearest signals yet that what lies beneath the scale matters far more than the number itself....
AI Translates Light Microscopy Into Electron-Microscope Detail to Speed
10+ min ago (534+ words) Mapping the wiring of the brain at nanometer resolution has long demanded a punishing trade-off: electron microscopy can reveal every synaptic cleft and organelle, but imaging even a cubic millimeter of neural tissue this way takes months or years of…...
Income Protects Breast Cancer Survivors From Heart Disease Unequally,
39+ min ago (101+ words) Higher income has long been treated as a reliable shield against chronic disease, but a sweeping new analysis of female breast cancer survivors in the United States suggests that this protection is anything but uniform. Drawing on four years of…...
Scientists Reveal How Rogue Antibodies Attack the Brain Protein IgLON5
43+ min ago (580+ words) A rare and devastating form of autoimmune encephalitis has long puzzled neurologists: patients develop severe sleep disturbances, breathing difficulties, and progressive movement and cognitive problems, yet the underlying attack on the brain remained poorly understood at the molecular level....
Therapeutic Vaccines for Ovarian Cancer Show Promise but Remain Stuck in
51+ min ago (83+ words) Ovarian cancer remains one of the most lethal gynecologic malignancies, and for decades researchers have pursued an idea that sounds deceptively simple: train the patient’s own immune system to recognize and destroy tumor cells. A new analysis of the entire…...
Engineered Bacteria Turn Nitrogen Gas Into L-Glutamate in Fermenter
53+ min ago (56+ words) A team of researchers in Japan has coaxed two bacteria working together to make one of the food industry’s most important amino acids directly from nitrogen gas, a feat that could loosen the grip of the energy-hungry Haber–Bosch process…...