3+ day, 12+ hour ago   (358+ words) Genetic Engineering and Biotechnology News Manus, The BioAlternatives Company®, and the University of Texas at Austin say they have completed a BioMADE-sponsored program to make industrial yeast fermentation more efficient and sustainable. The project, carried out with Hal Alper, PhD,…...

3+ day, 15+ hour ago   (433+ words) By Mike May, PhD A key to modern media optimization comes from knowing that different cell types need different media. [Westend61 / Getty Images] Cell culture has come a long way since then. That complexity was the focus of a recent discussion…...

4+ day, 14+ hour ago   (315+ words) AstraZeneca researchers show that automated microscale chromatography can generate process-characterization insights comparable to traditional bench-scale systems, potentially giving bioprocess developers a faster, material-sparing route to robust manufacturing control strategies for complex biologics. The post Microscale Chromatography Moves Toward Manufacturing Readiness…...

4+ day, 14+ hour ago   (422+ words) By Gareth John Macdonald Credit: AscentXmedia / Getty Images Autologous cell therapy production is difficult from an operational standpoint, according to researchers, who say choosing a manufacturing model that addresses the specific logistical and economic challenges of the project involved is…...

4+ day, 14+ hour ago   (165+ words) Overexpressing the cytoplasmic poly(A)-binding protein gene Pabpc1 increases protein titers in Chinese hamster ovary (CHO) cell lines by 30–50%, according to researchers from BeOne Medicines (formerly BeiGene). Those results, published in a recent paper, appear consistent across multispecific and monoclonal antibodies....

5+ day, 12+ hour ago   (208+ words) Sponsored content brought to you by VSV-G is the surface glycoprotein of the vesicular stomatitis virus. VSV-G-pseudotyped lentiviral vectors are widely used for gene delivery, offering broad tropism, substantial transgene cargo capacity, and ease of production. But broad native tropism…...

5+ day, 14+ hour ago   (302+ words) ProBioGen and Transgene report that they broadened the scope of their existing collaboration to include an additional license agreement for ProBioGen’s suspension AGE1.CR.plXR cell line which is designed to boost Transgene’s manufacturing capabilities with this specialized production technology. ProBioGen…...

5+ day, 15+ hour ago   (52+ words) Sponsored content brought to you by 1. Clarke H, et al. Biotechnol Prog. 2024:e3449. doi:10.1002/btpr.3449. 2. Diep J, et al. Biotechnol Prog. 2021;37:e3192. doi:10.1002/btpr.3192. 5. Corrigall H. Bruker Cellular Analysis webinar, 2025. Eric Sackmann, PhD, is a director of product management at Bruker Cellular Analysis....

1+ week, 1+ day ago   (259+ words) NewBiologix will use its Xcell™ stable manufacturing platform to generate and characterize a research cell bank for Synastra’s DMD gene therapy candidate. The agreement also provides an option to transition the program to a commercial license supporting future clinical and…...

1+ week, 3+ day ago   (247+ words) Watchmaker Genomics signed a long-term lease for approximately 100,000 square feet at Flatiron Park in Boulder, CO. The facility will more than double Watchmaker’s manufacturing capacity and provide room for continued growth across R&D, quality, logistics, and other key functions....